INITS Chose Sartorius Bioreactors Technology for its disruptive bioproduction facility

Montpellier, France, February 2026 - INITS, an innovative French biopharmaceutical service company, is pleased to announce a collaboration with Sartorius, a global leader in bioprocessing solutions. Through this partnership, INITS will equip its upcoming bioproduction facility in Mauguio with a continuity of Sartorius bioreactors — from small-scale development systems to large-scale single-use stirred-tank reactors.

The installation includes Biostat® B Twin CC systems with 2 L and 10 L Univessel® glass or single-use vessels (2L) for R&D activities, as well as Biostat STR® Generation 3 single-use bioreactors at 50 L and 200 L for GMP clinica l manufacturing.

Why Sartorius?

Sartorius is a longtime partner for companies in biopharmaceutical development, offering equipment, services, and instrumentation tailored to industry needs. Their equipment is fully integrated into INITS' SMO model, which is designed to be flexible and multi-product.

R&D Scale – Biostat® B Twin CC (Glass) / Univessel®

• 2 L and 10 L glass stirred vessels (Univessel® Glass CC) for process transfer, optimization, and scale-down studies.

• Flexible controller supporting multiple vessel types (glass, single-use), with full DO, pH, temperature, level, sparging (air, O₂, N₂, CO₂), and feed control capabilities.

• Univessel® SU 2 L (single-use): perfectly suited for eliminating risks of cross-contamination, with pre-sterilized disposable culture vessels and integrated DO and pH sensors.

These systems are proven and reliable design used by thousands of laboratories worldwide and have flexible configuration for mammalian, insect, or plant cell culture.

Pilot / GMP Scale – Biostat STR® Generation 3 Single-Use

• Two 50 L STR® Generation 3 reactors: adapted for intermediate process production or transfer, scale-up experiments.

• Two 200 L STR® Generation 3 reactors: to support GMP clinical manufacturing.

• Each STR reactor is operated with Flexsafe® STR single-use bags and controlled via the Biobrain® platform, featuring full GMP-ready functionalities (audit trail, user management, batch reporting, and data archiving).

These systems improve productivity and ease of use with SU technology, integrated sensors (pH, DO, foam, …) and Flexsafe STR bags.

They offer seamless scalability, with geometric similarity from 50 L to 200 L, ensure reliable scale-up while preserving process performance.

A Major Step Forward for INITS’ SMO Concept

INITS SMO’s facility — operational in April 2026 — is designed to bridge a critical gap in the biopharmaceutical landscape: offering biotech companies the ability to produce their own GMP DS batches, while benefiting from all the support needed (Project Management, Training, Regulatory, Quality Assurance, Quality Control, Supply) to ensure GMP compliance.

Equipping the site with Sartorius’ proven bioreactor platforms ensures:

• End-to-end scalability from lab scale to GMP scale

• Operational efficiency thanks to single-use systems and integrated sensors

• Regulatory readiness, with full audit trail, batch data management, and compliant automation

• Flexibility to accommodate multiproduct activities and diverse therapeutic modalities

  
  

A big thank you to the Region and the European Union for their financial support: European Commission La Région Occitanie / Pyrénées-Méditerranée.